Spiders are aggressive Monsters that live in Spider Dens. They can also be spawned from a Spider Queen.They are generally nocturnal; only coming out in daylight if their den is attacked, or if the webbing from their dens is stepped on. Spiders are generally found wandering alone but will join together if one of them is attacked. When killed, all types of Spiders drop Monster Meat, Silk or Spider Glands (valuable resources used in crafting and for healing).
Spiders found wandering at Night can easily be killed with melee weapons. When hit, Spiders will be stunlocked and unable to attack for a few moments, during which they can be hit again. After the first Spider is hit once other nearby Spiders will defend it. If they are far enough apart each Spider can be quickly killed before the others are in range. If the player is being chased by multiple Spiders close together he/she can kite them. This involves striking a Spider and then running out of range before other Spiders can attack. Over time each Spider will be hit multiple times and killed.

[ Register or Signin to view external links. ] [ Register or Signin to view external links. ]

At Night, most Spiders will leave their dens. Larger dens, however, contain many Spiders (Tier 2 and 3 dens spawn Spider Warriors), and only a few leave at a time. When one of these Spiders is killed, another Spider will emerge to take its place. Killing these Spiders as they leave will slowly empty the den and allow it to be destroyed. Emptying a den in this manner will also prevent the spawning of Spider Warriors, who will spawn if the den is attacked before it is empty. Another way is to step on the webbing which will cause some Spiders to emerge (just like during daytime) and then run away. The Spiders won't go back into the den if it's dusk or night. Doing so will not cause Warriors to spawn. If all Spiders are finally outside, you can easily destroy their den because this will not aggro them.

Due to a spider being able to be stunlocked Wendy can use this to her advantage with Abigail, as her attack is frequent and can hit more than 10 spiders at once, allowing the spiders to be killed swiftly and quickly with little to no damage to Abigail. It is best to attack the spiders at dusk or Night so as to deal the most damage to them.

When fighting spiders along with pigs they can eat the spoils of the battle (Meats and Pig Skins) very fast, so when trying to gather resources you have to be fast and usually you can't manage to get what the pigs drop as they die to the spiders. Spiders can also be caught in small animal Traps. When placed on the ground Traps can be baited with any meat, even that which was gathered from their fellow Spiders, to lure in a Spider. Alternatively, Spiders can be lead into unbaited traps once they start chasing, as they will not try to dodge them. One way to clear a Spider Den is to place several Traps and lead the Spiders (and Spider Warriors) into them after attacking the den to stir them up.

You can also place a Lureplant by the Spider Den and surround it with walls except for the plant and the spiders will sometimes go to it. Though the Lureplant will pick up the Monster Meat it drops.

Another way to farm them requires you to go into caves to get some Bunny Puffs. Once you get them, use them to build Rabbit Hutches around a den (at least 4). During dusk and night the Bunnymen and the spiders will fight each other, with the bunnies winning. You then can gather all the materials at dawn. This is better than using Pig Men since the Bunnyman won't eat the monster meat dropped by spiders.