I do NOT take credit for this guide, I found this on another forum and am simply sharing to help fellow TTG GTA'ers. With that being said, below is a description of every heist, including steps, strategy, and rewards.

**Spoilers Ahead if you don't want to see what they are all about**

First Heist: FLEECA BANK

1st Setup (SCOPE OUT): Basically go scout the Fleeca Bank with Lester. He'll give one of the teammates a program that allows him/her to unlock and open the vault door from outside of the bank. It's just used for practice. Kinda like a minigame for the passenger to mess around with. It'll also help if the passenger in this setup plays as the driller in the actual heist since he'll be familiar with the hacking device. After scouting the bank, go to Lester's factory and pick-up Paige. Take the Granger back to you apartment. MISSION COMPLETE.
REWARDS:
PAYOUT: Normal: $115,000 Hard: $143,500
ELITE CHALLENGES: -Complete in under 5:20
-Car sustains 6% damage or less
-No one gets wasted.

2nd Setup (KURUMA): Go to the parking lot around the Del Perro area and crash a Korean gang's meeting. Take the armored Kuruma back to Leter's factory. Payout will depend on the condition of the car upon delivering it. MISSION COMPLETE.
REWARDS: NONE
PAYOUT:

Heist (FLEECA BANK): 1 Driver and 1 Driller are required. Go to Lester's factory and pick-up the armoured Kuruma. Driver will...uhm...drive to the Fleeca Bank. Driller will hack the vault door on the way there. Once at the bank. Driver will destroy all 4 cameras. (1 directly to the left upon entering, 1 directly to the right of the door and 2 in the small hallway to the vault door. Driver just intimidates the hostages while Driller takes the money. (I haven't been able to play as the driller because I always get disconnected, so I don't know exactly what he does.) Afterwards, the driver and driller drive to the Zancudo Bridge to get picked-up by the Cargobob. Just simply drive at the same pace as the Cargobob/stay under the giant magnet. MISSION COMPLETE.
REWARDS: Unlocks Karin Kuruma ($95K) and Armored Kuruma ($525K) in the Southern SA Super Autos website.
PAYOUT:

Second Heist: PRISON BREAK

1st Set-up (PLANE): Go to the Mckenzie Airfield and steal the Vellum plane there. There will be 2 teams. 1 team is mainly gunners (3 players) and 1 team is the pilot (1 player). Simply kill all the Vagos there. After that, the pilot will take the Vellum to LSI and deliver it. All other players will be left at the airfield to kill any other Vagos there. MISSION COMPLETE.
REWARDS: NONE
PAYOUT:

2nd Setup (BUS): Go to the prison out in the Senora Desert and steal the prison bus. The bus has a FIB Buffalo and a Police Maverick as it's convoy/protection. Simply kill the driver and steal the bus. After stealing the bus, you'll need to lose the cops. The easiest way to do so is to go off-road to where cops will barely spawn. Also, if you're riding with a passenger, it'll be a whole lot tougher to get rid of the cops because the you'll never be able to to lose them or get out of their line-of-sight even if there are no cops around. After losing the cops, take the bus to the junkyard in the Grand Senora Desert. MISSION COMPLETE.
REWARDS:
PAYOUT:

3rd Setup (STATION): 2 teams. 1 team goes to the police station at Downtown LS. They will need to steal a police cruise and pose as cops to get the inmate transport schedule. Other team goes to the docks and boards the Cargo ship. Kill all enemies that and scale the cargo containers at the back of the ship. Shoot the padlock of the container with the Cargo in it and drive it off the ship. Lose the cops and take it back to the driver who's waiting out in the Senora Desert. MISSION COMPLETE.
REWARDS: Unlocks Lampadatti Casco in the Legendary Motorsport website.
PAYOUT:

4th Setup (WET WORK): 2 teams. 1 team goes to the city hall and kills the lawyers. Other team goes to a mansion to kill a specific target. The team should be silent and sneaky, killing all the guards before you are caught in their line-of-sight. If you are seen by them, they will alert everyone else and the target. Once alerted, the target will run away on foot. You must kill him before he reaches a certain distance or else he will disappear. The team that will kill the lawyers will need to take the deposition and will be wanted by the cops. Once they have lost the cops, everyone will meet up at the apartment where the mission was started to deliver the deposition. MISSION COMPLETE.
REWARDS: NONE
PAYOUT:

Heist (THE PRISON BREAK): 3 teams. One player is the pilot, one player the demolition, and a pair of players teamed as an inmate and prison guard. The pilot heads to the airport to fly the 5 seater velum, acquired from the previous setup mission, to the big airfield in Sandy Shores. Meanwhile the prisoner/guard team head to the junk yard in Sandy Shores, to get into the prison bus from the previous setup mission, while the demolition player heads north to intercept the actual prison bus that is heading to Bollingbroke prison. The demolition goes to Sandy Shores Arifield and destroys the prison bus, then heads to the airfield for the next part of the mission. The prisoner/guard team drive the bus to the prison. Upon approach to the airfield, the pilot receives an alert that jets have been scrambled to shoot down the velum. The demolition player acquires a buzzard to defend the velum from the lazers that spawn. Once inside the prison, the prisoner/guard team become discovered and begin a shootout with the prison guards while making their way to acquire the prisoner. Once acquired, the prisoner will follow his rescuers. After taking out all the guards, the rescued prisoner and the team get into the armored vehicle in the front of the prison and exit the same way they came in, heading to the airfield where the pilot has landed and awaits. The rescued inmate, and guard/prisoner team get into the velum and take off while the demolition remains in the buzzard to help the velum escape. The pilot must escape the 5 star wanted level then hit the marker to trigger a cutscene of everyone except the rescued prisoner, jumping out of the plane and landing on a beach to be picked up by the demolition in the buzzard and flown back into town. Warning: there is a glitch where you can't lose your wanted level/the cops when there is more than 1 person in the vehicle. No current full-proof way to solve it, but just hope that you're lucky enough. MISSION COMPLETE.
REWARDS: Unlocks the 5-Seater Vellum plane ($995K) in Elitas website. Also unlocks the Prison Bus ($550K) in the Warstock Cache and Carry website.

Third Heist: HUMANE LABS RAID

1st Setup (KEY CODES): 4 teams. 2 lookouts. 1 bodyguard and 1 buyer. All 4 teammates will go to the parking lot near Simeon's car shop. 2 lookouts will get to their respective positions while the buyer and bodyguard will stay and wait for the "vip"/"seller." Once they come, a cutscene will be played showing the FIB crashing the exchange. Kill all the FIB agents and take the briefcase. Take the briefcase back to the apartment. MISSION COMPLETE.
REWARDS: NONE
PAYOUT:

2nd Setup (INSURGENTS): All 4 players will go to the quarry. Once there, kill all the Merryweather agents there and take the 2 Insurgents (1 is the pickup with the turret and the other is the regular Insurgent). It would help if the 2 vehicles travel together since there will be 2 attack helicopters with miniguns and rockets firing at the vehicles. Deliver the 2 vehicles to the marked location and kill all the remaining Merryweather agents following you. MISSION COMPLETE.
REWARDS: NONE
PAYOUT:

3rd Setup (EMP): All 4 players get on a Dinghy and head to the aircraft carrier out in the ocean. Upon boarding the ship, the team will make it's way up to the top of the carrier. Once the team killed all enemies in the first area and is told to take the stairs, don't go to the door nearest to the stairs. Instead, go to the first door after turning right. Just follow the route up to the top. Once you've made it to the top of the ship, kill all enemies there and one person must take the Hydra. All other players will take P996-Lazers to help fight off enemies jets trying to take down the Hydra. After disposing of all enemy jets, take the Hydra to the Sandy Shores Airfield. MISSION COMPLETE.
REWARDS: Unlocks the Mammoth Hydra ($3 million) in the Warstock Cache and Carry website.
PAYOUT:

4th Setup (VALKYRIE): The team will go to a Merryweather base near the doacks (where the Casco team had to go) and steal a Valkyrie. The place is loaded with Merryweather agents everywhere, so use caution when getting to the Valkyrie. I was able to get to the chopper by going to the right side of the building and just running on the edge of the building. Surprisingly, I didn't fall into the water and no one was able to hurt me until I got to the back of the building. Once everyone has boarded the Valkyrie (1 pilot, 2 minigun gunners on the side and 1 explosive turret gunner in the passenger seat beside the pilot), the helicopter will takeoff and will be chased down by 5 helicopters. First wave is 3 choppers, next wave is another 2. Afterwards, deliver the Valkyrie. MISSION COMPLETE.
REWARDS: NONE
PAYOUT:

5th Setup (DELIVER EMP): Take the Insurgent to the Humane Labs and use stealth to take out the enemies. It's pretty difficult because the enemies and scientists are easily alerted and you'll fail the mission if someone gets alerted of your presence. Kill all the enemies that are marked on the minimap and hack the console. You'll leave the Insurgent there and you can take the small truck beside the garage. This truck fits 4 people. 2 in the front and 2 in the back. Just make your way out of the Humane Labs area. You wont encounter any sort of resistance unless you provoke them, I guess. MISSION COMPLETE.
REWARDS: NONE
PAYOUT:

Heist (THE HUMANE RAID):
REWARDS: Unlocks Valkyrie Attack Helicopter ($ ), HVY Insurgent ($675K) and the HVY Insurgent Pickup (1.750 million) in the Warstock Cache and Carry website. Also unlocks Night Vision Goggles and Rebreather in Ammunation.

Fourth Heist: SERIES

1st Setup (COKE): There will be 2 teams, team helicopter and team boat. Just as the team names suggests, one team will take a helicopter and land it on the frat boys' yacht just off Del Perro beach. The other team will take a boat to the yacht. All 4 members will then fight off all the enemies on the boat and take the packets of coke. Once all packets are collected, all players must get off the boat and lose the cops. They'll all meet Ron under a bridge/freeway at East Vinewood. MISSION COMPLETE
REWARDS: NONE
PAYOUT:

2nd Setup (TRASH TRUCK): 2 teams once again. The collectors and the operators. All 4 player will board a trash truck and go to different areas collecting trash. Collectors will go and collect the trash bags while the operators will protect them. There will be 4 different collection areas. The first one will have no Vagos present, so the operators can chill in the trash truck and let the collectors do their job. The second, third and fourth area all have Vagos in the area, so the operators really need to protect the collectors. Once all trash bags are secured, the team will head back to East Vinewood to meet Ron. Be careful when going to East Vinewood. There will be a lot of Vagos vehicles chasing you which this could cause a lot of deaths, and also cause the failure of the setup. Be prepared for this part. MISSION COMPELTE.
REWARDS: NONE
PAYOUT:

3rd Setup (BIKERS): This mission is all about stealth. At the start, you'll be prompted by Trevor to go to his trailer and pickup some silenced weapons. Then you'll need to take a Dinghy to the Lost MC camp. Now, just like the previous heist setup, Deliver EMP, this setup requires you to be really stealthy. The order that we did was, kill the lone guy knocking on the door immediately as you get on the beach. He won't alert anyone and he's really easy to kill. The next target you'd want to kill is the guy sitting down in front of one of the trailers after the guy walks past him. After him, there will be another walker and you'll need to gun him down as well. The next targets are the 2 guys chatting by the far left of the map. The enemy walking/walker around would've past them already and you'll need 2 people to cooperate for the kill (you'll need to go all the way around to avoid being spotted.) After those 2, wait for the walker to come back around and kill him. The last 4 people need to be taken out together. The 2 on the stage can be easily killed via collateral if you work your away around to the beach, close to where you started. After all enemies are killed, you'll take the 2 Gang Burritos and bring them back to East Vinewood. MISSION COMPLETE.
REWARDS: NONE
PAYOUT:

4th Setup (WEED): The team will go to the sawmill area and take a Karin Rebel from the Vagos there. There will be 2 lookouts who will help gun down majority of the Vagos since the ground team will probably die doing so. After all the Vagos are killed, 2 people will take the Karin Rebel and protect the drivers driving the vans from any Vagos attempting to kill them. Deliver the vans and Rebel to the warehouse in East Vinewood. MISSION COMPLETE.
REWARDS: NONE
PAYOUT:

5th Setup (STEAL METH): All Team will head to the ONeil Brothers Farm & steal the tanker full of meth. Once there clear out the house full of rednecks (Interesting to note, when we died and restarted it spawned us in-front of the tanker with NO enemies.) Drive it back to the gas station and defend it as rednecks will continuously attack until you arrive (You can have someone stand ontop of the tanker and shoot, so long as you don't flip it you will not fall off).


Heist (SERIES A FUNDING): This heist is surprisingly straight forward. Protect the warehouse from the Vagos with 2 teams, north and South lookouts. After that, 2 players will drive the 2 modified Mules while the other 2 players will man the Karin Technical and protect the Mules (both Mules have their own health bars, so you'll need to closely monitor that.) The Mules and the Rebel will make their way to Grapeseed and stop at the house beside the lighthouse. After that, a cutscene will play, showing Trevor paying the heist crew. MISSION COMPLETE.
Another cutscene, but it's a spoiler.
Spoiler
Another cutscene will play, showing what happened with the deal. The buyer was actually an undercover FIB agent and Trevor jumps off the cliff and into the water. Afterwards, he escapes the scene.
REWARDS: Unlocks the Karin Technical ($950K) and the Mule ($32.5K) in the Warstock Cache and Carry website.
PAYOUT:

Fifth Heist: PACIFIC STANDARD

1st Setup (VANS): This setup is all about teamwork and cooperation. There will be 2 teams; a team of navigators and a team of drivers. The navigators will need to be in the passenger seat of one of the driver's cars and will guide the driver to where the Post-Up trucks are located using a Tracking app on the phone. Navigators will not need mics as the game will aallow you to navigate using the d-pad, similar to how the navigator will navigate the driver in a rally race. The team will need to locate a total of 4 trucks around the San Andreas area (for my team, one of them was roaming around Del Perro, 2 were roaming around the LSC near the Eclipse Towers and the last one was near the La Puerta area. Hopefully, it's the same for you guys as well.) Each truck that you find will have a license plate that you need to photograph, be careful also when doing this mission since you can spook the drivers and fail the mission. After you photograph the license plates and send them to Lester, you'll need to steal of the trucks (for us, we needed to get one near the LSC.) Then, you'll deliver the truck to Lester's factory, same place as where you delivered the Kuruma in the first heist. MISSION COMPLETE.
REWARDS: Unlocks the Brute Bosville ($45K) in the Warstock Cache and Carry website.
PAYOUT:

2nd Setup (SIGNAL): All members will have to go pickup some Seasharks (Jet Skis) just off the coast of Chumash and take them to an island in the Paleto Cove area. Once there, you'll need to kill all the police agents there and rescue a hermit named Avi Shwartzman. The player who approaches the house first will be the one who Avi will follow around and will ride a Police boat with him. The other 3 players are given 2 Seasharks to help deliver Avi to Grapeseed. You'll be given 8 minutes to reach your destination or you'll fail the setup. Once you're all going, head straight for the really narrow river that cuts through the mountains near Mt. Chiliad. Make your way to Grapeseed and immediately ground the boat once you reach the shoreline near the runway area (more specifically, there's a bridge near the runway, if you look on the map, the Alamo Sea will have a small streak go into the island. That's where you'll want to stop the boat.) Near the bridge will be a parking lot, so the 1 of the players on a Seashark will go get a car for Avi and the player he's following. The player who's driving the police boat should just camp under the bridge while everyone else kills all the cops coming towards the area to allow him to lose his wanted level (the player with Avi is the only one who really needs to lose the cops.) Once he's lost his wanted, he'll take a car and driver Avi to the marked area. No one else should get in the car or else he'll gain wanted level again. MISSION COMPLETE.
REWARDS: NONE
PAYOUT:

3rd Setup (HACK): In this setup, there will be 2 teams; the Decoys (3 players) and the Transporter. All 4 players will make their way to Lester's factory to pickup a white Burrito. Then, they'll go to the Vinewood area and fight off a bunch of gang members, making their way to a black Gang Burrito. Then, a cutscene will play, showing the Transporter transferring the 'magic box' from the Gang Burrito to the white Burrito. Afterwards, the Decoys will take the Gang Burrito to the Del Perro area to lure the gang members away from the Transporter. The Transporter will take the white Burrito with the newly installed 'magic box' back to Lester's factory. MISSION COMPLETE.
REWARDS: Unlocks the Declasse Gang Burrito ($65K) on the Southern SA Super Autos Website.
PAYOUT:

4th Setup (CONVOY): Youll be intercepting a convoy (2 Merryweather Mesas, 1 military Barracks, an armed Insurgent and a Savage attack helicopter.) This will take place near the Lost MCs camp. When you get to the bridge, youll immediately see that there is a red helicopter symbol on your minimap, heading over the mountains. My tip here is to pull out a Heavy Sniper and shoot where the pilots supposed to be seated (which is in the middle) until you see the helicopter just explode. Thats your indicator that youve killed the pilot. Once the convoy comes, kill off all the enemies, but dont blow up the Barracks and the Insurgent. Youll need those to complete the mission. Have 2 or 3 people man the Insurgent and protect the other player who will be driving the Barracks. It will be difficult to escape Merryweather, so be prepared with a lot of snacks and extra body armor. There will be a total of 3 Savages that will chase you down as you make your escape, so destroy them quickly. Youll then deliver the Barracks to Paige in Grapeseed. MISSION COMPLETE.
REWARDS: Unlocks the Savage Attack Helicopter ($1.95 million) in the Warstock Cache and Carry website.
PAYOUT:

5th Setup (BIKES): Really straight forward mission. Go to the Lost MC Clubhouse and kill all the gang members there. Take the 4 Lectro motorcycles and deliver them to an alleyway in Downtown Vinewood. MISSION COMPLETE.
REWARDS: NONE
PAYOUT:

Heist (PACIFIC STANDARD): In this heist, youll be robbing the Pacific Standard Deposit Public Bank. The team will makes its way to the bank and enter it. There are 3 teams for this; Crowd Control, Hacker and Demolition. Hacker and Demolition will do majority of the work in the bank, similar to the job of the Driller in the Fleeca Bank Heist. The players on Crowd Control will make sure no one sets off the alarm. Once youve successfully taken $1.2 million, the team will meet at the entrance of the bank. After that, youll need to fight your way to the alleyway where you stored the Lectro bikes. After that, you make your way to Raton Canyon to use the Dinghy. Instead of using the Lectros (because people are bound to fall off and die), turn left out of the alleyway and head for the roadblock with the 1 police car and the makeshift ramp. All 4 players will ditch their Lectros and get in the police cruiser then make their way to the objective. It will make life a whole lot easier for the whole team because people will be prone to dying a lot less. The route that youll take will be going through Mt. Chiliad Park, so be careful here. At the end of the route, youll ramp your car off the mountain. Bail out of the car immediately and activate your parachute then head for the Dinghy thats parked there. Once all of the members are in the Dinghy, just drive to the waypoint and youre home free. MISSION COMPLETE.
REWARDS: Unlocks the Principe Lectro ($750K) in the Legendary Motorsports website.
PAYOUT:

EXTRA: "You Can't Touch This" T-Shirt can be unlocked after doing any of the 5 heists (not setups) without taking damage.



Hope this helps!