Walking around a corner right into a super mutant with a missile launcher, seeing said missile fly by my head, running away and ordering Danse to go first. "NOOOOOPE NONONONO. Danse, youre up buddy!"

There's a quest called 'The Devil is Due' or something like that, I'm not going to spoil it but I recommend doing it because its really creepy but cool, make sure you have a powerful weapon though before doing it.

The end of this quest is probably my biggest nope moment.

When I was walking into the glowing sea to find virgil the music got all intense so I know something was happening but I didn't know what. I turned around and all the sudden there was 4 deathclaws running towards me! *Pulls out fatboy* haha.

I remember one time I was walking around and I didn't hear a ghoul coming until he was like 5 steps away, I turned around and yelled out loud at like 2 AM. Pretty sure I woke up my parents.

When I fast traveled to a police station for the holotapes I spawned and their was a Assultron Dominator and I instantly died I haven't faced one since I had it recorded on my xbox 1234((

When I walked into the Hubris Comic Book store and discovered the massive ghoul nest.

Walking past a truck and an Legendary Assultron dominator came around it and blew it's self up after I shot it a bit, it was pretty much like a mini nuke blowing up in my face.