That is going to depend on tire width and wheel offset. Generally speaking with a "normal" set up (I.E not deep dish wheels with 15.5" wide tires) they'll fit, but with stock tires and 35.12's you will be fine. You could run that set up on a 2.5" leveling kit. I will warn you though, with 35's your trucks speedo will be off, the truck will have little to no power, and you're putting a ton of strain on the transmission. The only way to fix this is if you re-gear your diffs (front and rear if 4x4, just rear if 2wd). This will cost about $2500-$3k. Can you run a truck on stock gears? Sure. Will it lead you problems? You bet. Will it be imminent that the second you run 35's your tranny will blow up? No. I ran 35's on my old F-150 for a couple years before the torque converter went.

Also keep in mind that you'll be replacing front end components like your ball joints, ti-rods, CV axles, and wheel bearings VERY often. Stock your truck was meant to carry roughly 75 lb tires. My set of 30x12.5R17 on 17x9 wheels weighed 120 lbs. Now you're adding 45 LBS onto each wheel and suspension components don't like that lol. I replaced CV axles and wheel bearings once a year, ti rods and ball joints probably every 6-8 months or so.

002 obviously summed up pretty much all you needed to know but I just wanted to add that I have a 6in lift with 35's and there is an ample amount of room so if you were thinking of going 6in's you might be able to fit 37's

UnrealApp wrote 002 obviously summed up pretty much all you needed to know but I just wanted to add that I have a 6in lift with 35's and there is an ample amount of room so if you were thinking of going 6in's you might be able to fit 37's

I personally wouldn't reccomend anyone go to 37's on an IFS just because the weigh so much lol. OP should do a SAS, and put Raptor fenders on then run 37's or even 40's. Garage goals....