This is probably my best Fallout moment: (I told this in another topic exactly the same as this)

Mine was probably when I was about a level 10 and just bought New Vegas. I had no good weapons and really wanted to get to New Vegas. I started running across the wasteland from Black Mountain and outran a few deathclaws, then I managed to kill a few raiders and friends whilst just running towards New Vegas. Suddenly there were loads of fiends all around me and I had pretty low health. I just kept running. I was so sure I would die and have to try all over. I ran round a corner and saw a row of men who I thought to be fiends. I swore. Then I suddenly noticed they were NCR and they drew the fire of the fiends and killed them all for me! I had ran all the way from Black Mountain to Camp McCarren It was pretty damn cool