The cursor is off center, jerky, erratic, disappears, does not respond properly, is upside down, etc.
The cursor or character movement is not responding properly.

Try recalibrating the Wii Remote Plus.
Check the Directional Sensor Functionality by holding the Wii Remote with the button side down. Without using much force, firmly tap the button side of the remote against the palm of your other hand. Doing this does not take a lot of force, so be sure not to tap the Wii Remote very hard.
Verify that the Wii Remote's pointer lens is free of obstructions and contamination (stickers, heavy smudges, etc.). The pointer lens is the tinted rectangle at the end of the Wii Remote.
Verify that the Wii Remote is being used between 3 and 10 feet directly in front of the TV.
Verify that the Wii Remote Jacket is securely in place on the Wii Remote. If the Wii Remote Jacket is askew, it might be partially blocking the infra-red sensor on the front of the Wii Remote.
Try a new set of batteries. Occasionally weak batteries can cause this type of behavior.
Re-sync the Wii Remote to the console.
Clear the syncs on the console.
Reset the Wii Remote.
Verify correct setup of the Sensor Bar.

Check the Directional Sensor Functionality by holding the Wii Remote with the button side down. Without using much force, firmly tap the button side of the remote against the palm of your other hand. Doing this does not take a lot of force, so be sure not to tap the Wii Remote very hard.
Verify that the Wii Remote's pointer lens is free of obstructions and contamination (stickers, heavy smudges, etc.). The pointer lens is the tinted rectangle at the end of the Wii Remote.
Verify that the Wii Remote is being used between 3 and 10 feet directly in front of the TV.
Verify that the Wii Remote Jacket is securely in place on the Wii Remote. If the Wii Remote Jacket is askew, it might be partially blocking the infra-red sensor on the front of the Wii Remote.
Try a new set of batteries. Occasionally weak batteries can cause this type of behavior.
Re-sync the Wii Remote to the console.
Clear the syncs on the console.
Verify correct setup of the Sensor Bar.