You will need to first remove the DVD drive. Simply hold the drive and lift up. You will notice that the Xbox 360's DVD drive uses a Serial ATA interface which keeps things very tidy compared to the original Xbox. At this point, remove both the power supply cable and Serial ATA cable from the DVD drive and then from the motherboard.
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Next, remove the RF unit at the front of the Xbox 360 by removing the small black torx screws using a T6 screwdriver. Then you must remove the plastic cover on the front of the RF unit by unlatching the top and bottom of the plastic cover. Once you have done this, you will reveal the third screw holding the RF unit to the chassis. Remove the last screw and pull out the RF unit. Lastly, remove the power connections for the fans. You can now lift the motherboard out of the metal chassis.
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